University of Southern California

Research

Animal Resources

Department of Animal Resources

lab-ratsThe Department of Animal Resources and the Institutional Animal Care and Use Committee assist faculty in preparing proposals and carrying out animal-based research and teaching activities at USC. Services include: clinical, surgical and diagnostic laboratory services, ordering drugs and supplies, animal orders and transfers and rodent euthanasia. Training programs in Animal Care and Use are also offered to principal investigators, staff and students, as well as education programs for Laboratory Animal Technicians.

Health Sciences Campus
Center for Health Professions 234
University of Southern California
Los Angeles, CA 90033-9004
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Gene Targeting & Pathology Core

The Genome Targeting and Pathology Core provides genetically manipulated mice for biomedical studies. Services include: conditional /tissue-specific knockouts, knockins & lentiviral transgenesis, tissue paraffin embedding and sectioning, routine H&E staining and genotyping of tail DNA.

Children’s Hospital Los Angeles
4546 Sunset Blvd
Los Angeles, CA 90027
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Transgenic/ Knockout Rodent Core Facility

The USC Norris Comprehensive Cancer Center Transgenic/Knockout Core Facility provides high-quality embryo and stem cell manipulation, microinjection and related services to the USC community, as well as non-USC researchers. Services include: gene targeting and the production of knockout rats and mice, transgenic mice, construction targeting vector design, preparation of DNA for injection and in vitro fertilization, re-derivation, and cryopreservation.

Health Sciences Campus
USC Norris Comprehensive Cancer Center
1441 Eastlake Ave. Room 5318
Los Angeles, CA 90089-9176
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Non-Parenchymal Liver Cell Core & Animal Core

The Research Center For Alcoholic Liver and Pancreatic Disease core laboratories supports center investigators and serves as a national resource. Animal Core services include: mouse intragastric (iG) and ad lib ethanol feeding models which produce clinically relevant pathologic spectra of ALPD; routine BAL and ALT measurements; non-parenchymal liver cell core services, terminal experiments and sample collection, as well as a Tissue Sharing and Training Program. Animal models include: Rodent iG Models Standard iG model; Hybrid model of Western Diet ad lib and Alcohol iG feeding for ASH with liver fibrosis; Hybrid plus Binge Model of Alcoholic Hepatitis and Alcohol/HCV Liver Tumor Models: Metabolomics Core services include: metabolomics analysis in animals and isolated cells, such as stable isotope-based (13C and 2H).

Health Sciences Campus
Mudd Memorial Research Building
1333 San Pablo Street, MMR 412
Los Angeles, CA
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