CIRM RFA-13-07: Alpha Stem Cell Clinics Network Coordinating and Information Management Center
Nomination per School: One
Proposals may not be submitted directly by the PI; nominations are submitted by the School’s Research Dean’s Office.
LOI: December 16, 2013 (Required)
Internal Deadline: November 25, 2013
External Deadline: Invitations for applications will be sent mid-January, 2014
Award Information: Anticipated Amount: CIRM intends to commit up to $15 million to support one award over five years. Given the urgency of CIRM’s mission, an approved application is expected to be initiated within three months of a grant start date that is indicated on a signed Notice of Grant Award, and must be initiated within six months of approval and authorization for funding by the Application Review Subcommittee of the Independent Citizen’s Oversight Committee (ICOC), CIRM’s Governing Board.
Materials to Office of Research: Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt).CV – (4 pages maximum)
Purpose: To accelerate therapeutic development and delivery of stem cell therapies, CIRM is establishing the CIRM Alpha Stem Cell Clinics (CASC) Network. This network will provide a high quality, efficient infrastructure to support clinical research emanating from CIRM’s funding pipeline as well as non-CIRM funded investigator- or industry sponsored trials with stem cell products being developed in California, or those developed worldwide and brought to California.
Under RFA 13-07, a single Applicant Organization will be funded for up to five years to provide supporting services to the Alpha Stem Cell Clinics (separately funded by RFA 13-06). The CIMC will provide critical inputs to the Alpha Stem Cell Clinics sites on trial design, data and information management, public and patient education and developing an evidence base to help sponsors achieve informed insurance decisions once their investigational therapies become approved. To promote the development of stem cell therapies worldwide, the CIMC will ensure maintenance and accessibility of valuable data and information relating to network clinical trials to the public, patients and the research community.
The CIMC’s key activities will be:
1) Clinical trial support
2) Data and information management
3) Outreach, education and training
4) Development of healthcare economics resources
The CASC Initiative consists of two linked Requests for Applications (RFAs) that will be co-released:
a) RFA13-06: Alpha Stem Cell Clinics Sites: Up to five clinical sites located in or affiliated with existing academic centers. (See RFA 13-06)
b) RFA13-07: Coordinating and Information Management Center (CIMC): One coordinating center to facilitate the efficiency and effectiveness of the network of clinical sites across California.