University of Southern California


RFA-OD-14-001 NIH Botanical Dietary Supplement Research Centers (BDSRC) (P50)

Slots:                                                     One per Institution                        
Nomination per School:               One
Proposals may not be submitted directly by the PI; nominations are submitted by the School’s Research Dean’s Office.    

LOI:                                                        April 6, 2014 (Not Required)
Internal Deadline:                           March 3, 2014
External Deadline:                          June 6, 2014

Award Information:                        Type:  New/Renewal
Estimated Number of Awards: The number of awards is contingent on NIH appropriations and the submission of a sufficient number of meritorious applications. ODS and NCCAM intend to commit an estimated total of not more than $10 million per year in total costs to support up to five awards.
Anticipated Amount: Application budgets may not exceed $1.25 million in direct costs but need to reflect the actual needs of the proposed project. The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Materials to Office of Research: Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). CV – (4 pages maximum)

Link to Award:

Purpose: This FOA seeks to enhance progress in the understanding of complex botanical preparations used for human health by supporting the development, or deployment from other fields, of cutting-edge techniques or approaches that will accelerate progress in botanical research, including contributing to the ability to rapidly assess the identity and potential of a botanical product for specific health-related bioactivities or for within or inter-product interactions. The renewed Botanical Dietary Supplements Research Centers Program is expected to significantly advance human or other animal health-related botanical research through multi-component, transdisciplinary Centers that bring together projects with the potential to contribute to one or more of the following objectives:

Preclinical projects focused on botanicals with a substantial history of human use, especially those used for health maintenance or improving resilience, are strongly encouraged, especially where focused on objective, quantitative outcomes with clear relevance to human health or resilience. Appropriate and translationally meaningful use of in silico, in vitro, and preclinical in vivo models, including invertebrate models, is strongly encouraged. At least one third of the Research Project specific aims should be focused on botanicals as they relate to resilience or health maintenance. These specific aims may be distributed among the proposed Research Projects as the investigators believe best suits the proposed research.

We anticipate that conduct of this research will include and entail: