University of Southern California


RFA-AI-20-036: Martin Delaney Collaboratory for Pediatric HIV Cure Research (UM1 Clinical Trial Not Allowed)

Slots:                                                     Only one application per institution is allowed to either this FOA or RFA-AI-20-035.

Internal Deadline:                             August 21, 2020, noon PT

LOI:                                                        November 6, 2020

External Deadline:                            December 7, 2020

Award Information:                         Type: Cooperative Agreement

Estimated Number of Awards: 1

Anticipated Amount:  Application budgets are limited to $3.5M in direct costs per year and need to reflect the actual needs of the proposed project. The total project period must be 5 years.

Who May Serve as PI:                    Standard NIH eligibility requirements.

Process for Limited Submissions: PIs must submit their application as a Limited Submission through the Office of Research Application Portal:

Materials to submit include:

(1) Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.

(2) CV – (5 pages maximum)


Purpose:                                              The objective of this FOA is to support a highly collaborative and synergistic research program focused on the development of research strategies suitable for pediatric populations to achieve either a sustained viral remission or complete eradication of persistent HIV reservoirs. Applications should support academic, industry, government, and community collaboration and partnerships.The application must include at least one private sector entity (defined below) to facilitate rapid translation of basic discovery research into therapeutic development and testing. The awardee will also be required to communicate and collaborate with the awards made under the companion Martin Delaney Collaboratory program. The proposed research should be innovative and must include a combination of basic, clinical, and applied research.

Examples of areas of research interest include, but are not limited to:

Target population for this FOA

Target populations include children, adolescents, and young adults living with HIV with perinatal infection age from birth up to 24 years of age. Children who initiated ART very early (within the 1st week of life) are of particular interest and access to this population is required.

Examples of anticipated outcomes/goals from the collaborative research:

The research proposed is expected to push the boundaries of what is currently feasible, and it is recognized that aspects of the plan necessarily will include high-risk research or development of improved methodology and technology. Development of combination treatment strategies or gene therapy approaches would be particularly suitable for this FOA.

Budgetary Requirements:              This FOA does not require cost sharing as defined in the NIH Grants Policy Statement.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.