University of Southern California


RFA-AI-20-030: Centers for HIV Structural Biology

Slots:                                                     1

Internal Deadline:                             June 18, 2021, 5pm PT

External Deadline:                            October 13, 2021

Award Type:                                       Cooperative Agreement

Estimated Number of Awards:     5-6

Anticipated Amount:                     $30 million

Who May Serve as PI:                   Standard NIH requirements.

Process for Limited Submissions: PIs must submit their application as a Limited Submission through the Office of Research Application Portal: PIs must create their own SurveyMonkey account in order to proceed with submission.

Materials to submit include:

(1) Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.

(2) CV – (5 pages maximum)

Note: The portal requires information about the PIs and Co-PIs in addition to department and contact information, including the 10-digit USC ID#, Gender, and Ethnicity. Please have this material prepared before beginning this application.

Purpose:                                              The purpose of this FOA is to support dynamic, multidisciplinary consortia of structural biologists, virologists, and computational scientists to resolve complex biological structures relevant to HIV prevention, treatment, and cure. The consortia are expected to leverage common resources, facilitate new collaborations, and engage and support the next generation of HIV structural biology researchers.

The goal of the Centers for HIV Structural Biology program will be to support teams of scientists to develop and utilize cutting edge technologies and methodologies to address the most challenging scientific questions involving the structures and functions of HIV-related macromolecular complexes. Centers are expected to move beyond the determination of static structures and into an understanding of the dynamics of complexes with an eye toward informing mechanistically based discovery and/or design of interventions for the prevention, treatment, and cure of HIV. The development of specific interventions is not the purpose of the FOA; rather, the goal is to establish new technologies and methodologies to facilitate the discovery of new therapeutic targets, elucidate the mechanisms of action of interventions, or determine the structural basis for interventional failures.

Budgetary Requirements:              Does not require cost sharing.

Visit our Institutionally Limited Submission webpage for more updates and other announcements.