NCI National Clinical Trials Network (NCTN) Program

Synopsis

These FOAs reflect the comprehensive effort by the National Cancer Institute (NCI) to transform the previous NCI-sponsored Clinical Trials Cooperative Group Program from supporting several individually operating Cooperative Groups into a new consolidated and integrated NCI National Clinical Trials Network (NCTN) Program. The overall goal for the entire NCTN Program is to conduct definitive, randomized, late phase clinical treatment trials and advanced imaging trials across a broad range of diseases and diverse patient populations as part of the NCI’s overall clinical research program for adults and children with cancer. The NCTN will also conduct, as necessary, smaller developmental studies preliminary to the definitive trials. The NCTN Program will be based on an integrated network of clinical trials groups that will collaborate with each other as well as with other NCTN components and other NCI-sponsored programs and investigators.

The NCTN Program will support the following components that will be individually awarded through the respective FOAs indicated below:

Institutional Limits and Program Information

For competitions:

NCI National Clinical Trials Network – Network Group Operations Centers RFA-CA-12-010 (U10) (up to 5 awards)
NCI National Clinical Trials Network – Network Group Statistics and Data Management Centers RFA-CA-12-011 (U10) (up to 5 awards)
NCI National Clinical Trials Network – Network Lead Academic Participating Sites RFA-CA-12-013 (U10) (30-40 awards)
NCI National Clinical Trials Network – Network Radiotherapy and Imaging Core Services Centers RFA-CA-14 (U24) (up to 1 award)
NCI National Clinical Trials Network – Canadian Collaborating Clinical Trials Network RFA-CA-12-504 (Limited Competition U10) (up to 1 award)

USC Slots: One
Nominations per school: One
Internal Deadline: November 5, 2012
Letter of Intent (LOI): December 15, 2012 (not required)
External Deadline: January 15, 2013

For competition:

NCI National Clinical Trials Network – Network Group Integrated Translational Science Centers RFA-CA-12-012 (U10) (5-7 awards)

USC Slots: No limit
Nominations per school: Not required
Internal Deadline: None
Letter of Intent (LOI): December 15, 2012 (not required)
External Deadline: January 15, 2013

Important Restrictions

PD/PI – MUST NOT be listed as PD/PI on other components below except as mentioned in the exception

• Network Group Operations Centers (RFA-CA-12-010);

Exception – If appropriate can be listed as key personnel on applications for its associated Network Group Statistics and Data Management Center and/or on the application for the Network Radiotherapy and Imaging Core Services Centers (RFA-CA-12-014), but not on the other applications and not on applications for other Network Group Statistics and Data Management Centers.

• Network Group Statistical and Data Management Centers (RFA-CA-12-011);

Exception – If appropriate can be listed as key personnel on the application for its associated Network Group Operations Center and/or the application for the Network Radiotherapy and Imaging Core Services Centers (RFA-CA-12-014), but not on the other applications and not on the applications for other Network Group Operations Centers.

• Network Lead Academic Participating Sites (RFA-CA-12-013);

Exception – They can be listed as key personnel

• Network Radiotherapy and Imaging Core Services Centers (RFA-CA-12-014);

Exception -If appropriate can be listed as key personnel on the applications for Network Lead Academic Participating Sites (RFA-CA-12-013), but not on the other applications.

• Canadian Collaborating Clinical Trials Network (-RFA-CA-12-504).

Exception – If appropriate can be listed as key personnel on the application for the Network Radiotherapy and Imaging Core Services Centers (RFA-CA-12-014).

Nomination Process

Interested faculty should contact their school’s dean of research who coordinate the first step in the internal selection process. Faculty are typically asked to submit, at a minimum, a CV or biosketch, as well as a single-page proposal summary to their research dean. Individual schools’ deadlines are in advance of the internal deadline posted above. Check with your school prior to our internal deadline for details concerning the nomination process.