University of Southern California


PAR-20-086: Biomedical Research Facilities (C06 Clinical Trial Not Allowed)

Slots:                                                     1

Internal Deadline:                           Contact the Office of Research if interested.

LOI:                                                        February 14, 2020

External Deadline:                          March 17, 2020, 5pm PT

Award Information:                        Type: Grant

Estimated Number of Awards: Not mentioned in proposal.

Anticipated Amount: $3,000,000 – $8,000,000

Submission Process:                     PIs must submit their application as a Limited Submission through the Office of Research Application Portal:

Materials to submit:

Link to Award:                        

Who May Serve as PI:                    The PD/PI should hold appropriate stature within the institutional administration structure and be able to oversee various facets of the entire project. The PD/PI should also demonstrate his/her leadership skills to recruit and guide expert Key Personnel with complementary scientific and technical skills to successfully plan, design, and accomplish the construction project.

Purpose:              This Funding Opportunity Announcement (FOA) invites qualified institutions of higher education to seek support to modernize and improve existing research facilities (e.g., laboratory space or animal facilities), or to construct new biomedical research space and furnish it with necessary fixed equipment. The objective of this FOA is to support the development of modern facilities that will enable and enhance the conduct of cutting-edge biomedical research. Any facility supported by this FOA must serve a broad research community, locally at the applicant institution or regionally.


Various factors are typically considered when developing or modernizing research infrastructure. For applications submitted to this FOA, defined research needs will drive the requests for modern engineering solutions. As science progresses and new technologies become available, required dedicated space must comply with relevant technical specifications to provide a well-controlled environment, to enable novel experimental approaches, and to house specialized equipment.


To appropriately conceive, develop, construct, and successfully complete the project, a Program Director/Principal Investigator (PD/PI) should possess knowledge of the relevant scientific field, have a vested professional interest in the success of the project, demonstrate leadership skills, and assemble a team with technical expertise related to all aspects of the project. The PD/PI does not need to be a currently NIH-funded investigator but should have the appropriate standing in the institutional administration and the research community to lead and oversee the project.

The project should be consistent with the following criteria and documentation requirements:

    • The project is essential for research activities supported and the space involved will be used for these activities.
    • The facility must be utilized for biomedical research purposes for which it was constructed or improved for at least 20 years beginning on the date of beneficial occupancy of the space.
    • If the project is located in an existing building, the building must have a useful life consistent with program purposes, including the time to construct and complete the project plus 20 years of use following the occupancy of the research space; the building must be architecturally and structurally suitable for conversion to the type of research space required.
    • If the space is rented, evidence must be provided that the terms of the lease and expected subsequent 20-year use of the facility are consistent with the proposed project. Specifically, a signed document from the building owner must be provided that the terms of the lease agreement and subsequent use of the facility will comply with the 20-year term of the Notice of Federal Interest (NFI) requirement following the occupancy of the facility. A statement of agreement by the owner of the space must be included. These documents will be verified if/when the application is considered for funding.
    • If the project will affect a site listed (or eligible for inclusion) in the National Register of Historic Places, the requirements specified in “Preservation of Cultural and Historic Resources” must be followed.


Budgetary Requirements:

The requested budget can support design, construction activity and purchase of fixed equipment and its installation costs. The fixed equipment may include infrastructure equipment, such as HVAC units serving the facility and other large fixed equipment connected to the building structure and services. Also, requests can be made for fixed laboratory equipment and its installation costs. Examples of such equipment include, but are not limited to:

    • fume hoods and laminar flow stations;
    • biosafety cabinets;
    • fixed casework and laboratory benches;
    • autoclaves and other sterilizing equipment.
    • Allowable costs also include:
    • appraisals;
    • bid advertising;
    • inspection and commissioning fees;
    • project management;
    • contingency fees (Allowable contingency fees are limited to 15 percent of the total allowable costs before bids are received and must be reduced to 10 percent after a construction contract has been awarded.);
    • filing fees for recording of Notice of Federal Interest (NFI).


Not-allowable costs include:

    • personnel costs not related to actual construction;
    • bonus payments to contractors;
    • consultant fees not related to actual construction;
    • damage judgement suits;
    • movable equipment;
    • scientific instruments (e.g., microscopes, scanners, spectrometers);
    • FDA approval process following the completion of the construction project;
    • F&A costs;
    • supplies;
    • fund-raising expenses;
    • interior and exterior decorating fees (e.g., purchase of artwork, sculpture, etc.).


Visit our Institutionally Limited Submission webpage for updates and other announcements.