University of Southern California


PAR-20-103: Collaborative Program Grant for Multidisciplinary Teams (RM1 – Clinical Trial Optional)

Slots:                                        1

Internal Deadline:                      October 9, 2020, noon PT

LOI:                                          30 days prior to the application due date

External Deadline:                     January 27, 2021

Award Information:                   Type: Grant

Estimated Number of Awards: The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Anticipated Amount: NIGMS anticipates supporting no more than 4-6 awards, corresponding to a total of $10,000,000 (total costs) for fiscal year 2021. Future year amounts will depend on annual appropriations and institute priorities.


Process for Limited Submissions: PIs must submit their application as a Limited Submission through the Office of Research Application Portal:

Materials to submit include:

(1) Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.

(2) CV – (5 pages maximum)

Who May Serve as PI:                               For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide.

The application is required to be submitted as a multiple PD/PI application, with a minimum of 3 and a maximum of 6 PDs/PIs, all of whom must have an appointment at a domestic institution. Scientists employed solely by foreign institutions may not serve as one of the PD(s)/PIs of the multiple PD/PI team, although they may be included in the application as collaborators/co-investigatorsconsultants or other significant contributors. Visit the multiple PD/PI Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide, and the Grant Policy Statement on Multiple Principal Investigators. Minimum allowed efforts by the PDs/PIs are described in the R&R Budget instructions in Part 2. Section IV.2.

Any eligible scientists with the interest and ability to develop a team science program to address an important research question are welcome to apply. NIGMS encourages the participation of early career investigators as part of the multiple PD/PI team with advising as appropriate. ESIs and new investigators who participate as a PD/PI will lose their early stage investigator or new investigator status for future NIH applications. ESIs supported by developmental funds in future years are not designated as PD(s)/PI(s) and will not lose ESI status. PD(s)/PI(s) who have an active NIGMS R35 award can participate as a PD/PI as part of the 51% effort on their current R35 award but may not receive additional funds from this award. Applicants with substantial unrestricted research support may receive funding from this award as their one NIGMS grant award, or may participate in an unfunded advisory or consulting role without loss of their ability to receive one funded NIGMS grant, consistent with NIGMS policies.

Purpose:                                               Many research questions in biomedical science can be pursued by single investigators and their close collaborators, and are adequately supported by individual and multiple PD/PI research grants. However, the scope of some scientific problems is beyond the capabilities of a small group of investigators. Such complex and challenging research questions benefit from the integrated efforts of teams of research laboratories employing complementary approaches and having multiple areas of intellectual and technical expertise, and the necessary resources to accomplish a unified scientific goal. Such team-based efforts can produce convergent, lasting scientific benefits with high impact, such as the creation of new disciplines of study, resolution of long standing or intractable problems, or definition of new areas that challenge current paradigms.

This funding opportunity announcement (FOA) encourages Collaborative Program Grant applications from institutions/organizations that propose to conduct research to address complex and challenging biomedical problems, important for the mission of NIGMS, through deeply integrated, multidisciplinary research teams. The Collaborative Program Grant is designed to support research in which funding a team of interdependent investigators offers significant advantages over support of individual research project grants. Applications should address critical issues and be sufficiently challenging, ambitious, and innovative that objectives could not be achieved by individual investigators.


Visit our Institutionally Limited Submission webpage for more updates and other announcements.