University of Southern California


PAR-20-107: Developmental Center for AIDS Research (P30 Clinical Trial Not Allowed)

Slots:                                                     1

Internal Deadline:                           Contact the Office of Research if interested.

LOI:                                                        June 29, 2020

External Deadline:                          July 28, 2020

Award Information:                        Type: Grant

Estimated Number of Awards: The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Anticipated Amount: A base of up to $1,000,000 total costs per center per year will be awarded. The scope of the proposed project should determine the project period. The maximum project period is 5 years.


Submission Process:                     PIs must submit their application as a Limited Submission through the Office of Research Application Portal:

Materials to submit:

Link to Award:                        

Who May Serve as PI:                    Standard NIH eligibility requirements.


The purpose of the D-CFAR is to provide support for applicants ultimately seeking a standard CFAR. A D-CFAR will allow the applicant to develop collaborations, to experiment with Core facilities that may be important to support HIV/AIDS investigators at the institution, and to build and strengthen any deficiencies that might adversely affect an application for a standard CFAR award, which could ultimately lead to the development of a competitive standard CFAR application.  The emphasis expected in a D-CFAR application will be the identification and clear description of gaps or deficiencies that would hinder development of a competitive CFAR application, and Core facilities that would reduce or eliminate these gaps. D-CFARs are intended to promote NIH HIV/AIDS research efforts at the D-CFAR institution(s).  The proposed D-CFAR priorities should align with the NIH HIV/AIDS priority topics of research for support using AIDS-designated funds (NOT-OD-15-137).

The D-CFAR program accomplishes this mission by:

Expected characteristics of all D-CFARs include:

    • Added value
    • Scientific and fiscal flexibility
    • NIH-funded HIV/AIDS investigators at the applicant institutions.
    • Collaborations with community groups, organizations, and other institutions.

NIH HIV/AIDS Funded Research Base (FRB) Requirement:

Institutions/Organizations with a HIV/AIDS FRB of $10M annually (minimum) are eligible to apply for a D-CFAR. The FRB is defined as the amount of Total Cost funding from NIH for one fiscal year (October 1 to September 30) preceding the calendar year of application submission.  D-CFAR applicants must maintain the required minimum FRB during the year of submission in order to be funded at the requested amount.  This applies only to competing applications.  The NIH HIV/AIDS FRB is compiled from data provided by the NIH Office of AIDS Research to determine eligibility. Applicants can request the FRB from NIAID.

The FRB includes NIH peer-reviewed HIV/AIDS research grants, program projects, and cooperative agreements utilizing the following mechanisms only:  DP1, DP2, DP5, R00, R01, R03, R15, R21, R24, R33, R34, R35, R36, R37, R56, R61, RF1, SC1, SC2, SC3, U01, U10, U19, U24, U34, UH2, UH3, UG3,  and K series awards. On a case-by-case basis, the following mechanisms will be considered based on whether or not the award involves primarily research activity:  KL1, KL2, N01, P01, P50, PM1, U54, UG1, UM1, UM2 and RC series grants.  Excluded from the NIH HIV/AIDS FRB are all funds from any source other than NIH.  Additionally, only the amount budgeted directly to an applicant institution(s) will be included for grants over $5M in the FRB.

Multi-institutional D-CFAR applications may combine the NIH HIV/AIDS-funded research of all the investigators at the institutions participating in the proposed D-CFAR to meet the NIH HIV/AIDS FRB eligibility.  A D-CFAR applicant cannot use the FRB of an institution that is already part of another CFAR or D-CFAR.  D-CFARs that use a distant institution for a core facility may not use the funded research of that institution if they are not including all of the NIH HIV/AIDS investigators at that institution as part of the D-CFAR.

Visit our Institutionally Limited Submission webpage for updates and other announcements.