University of Southern California


RFA-AG-21-024: Claude D. Pepper Older Americans Independence Centers (P30 Clinical Trial Optional)

Slots:                                                     1                             

Internal Deadline:                        Contact the Office of Research if interested.

LOI:                                                        September 29, 2020

External Deadline:                          October 29, 2020, 5pm PT

Award Information:                        Type: Grant

Estimated Number of Awards: NIA intends to commit approximately $5.2 million to fund 5 competing awards in FY21 and approximately $1.3 million to fund 1 competing award in FY22.

Anticipated Amount: Annual direct costs are limited to $950,000. The maximum project period is 5 years.

Submission Process:                     PIs must submit their application as a Limited Submission through the Office of Research Application Portal:

Materials to submit:

Link to Award:                        

Who May Serve as PI:                    Standard NIH eligibility requirements.


The Claude D. Pepper Older American Independence Centers (OAIC) program was established in honor of the late Representative to establish centers of excellence in research and research education to increase scientific knowledge leading to better ways to maintain or restore independence in older persons. See the NIA OAIC webpage for additional information about the program, application guidance, and answers to frequently asked questions.

The OAIC awards are designed to develop or strengthen awardee institutions’ programs that focus on and sustain progress in a key area of aging research. Applicants should identify an area of focus in which progress could contribute to greater independence for substantial populations of older persons and offer opportunities for education in aging research. This area of focus should be a common theme around which all proposed OAIC activities are organized. NIA’s expectation is that an OAIC, in a given area of focus, will:

Area of Focus

To achieve the objectives listed above, each OAIC should promote a sustained research program in an area of focus through which the Center will accomplish the innovation, leadership, collaboration, and research education functions described above. It is crucial to the design of an OAIC to identify an important research area to be addressed, to specify the goals to be achieved within the five-year OAIC award period, to provide a plan to reach these goals, and to outline a method to evaluate progress toward these goals during the course of the OAIC award. The selection of core activities (see below) should follow from these considerations.

An OAIC may select an area of research focus from a broad range of topics, including, but not limited to, the following:

In general, each research focus described above has the potential for a wide range of developmental and infrastructural activities that are likely to be interdependent and synergistic. Thus, an OAIC strategy of selecting several key activities that address its area of focus may have unique benefits.

As the level of funding for individual OAICs is unlikely to allow such a set of activities for more than one focus area, applicants are strongly encouraged to select an area in which their strengths allow their OAIC to fulfill NIA’s goal for the OAIC program and to direct their proposed OAIC activities toward that research area, while also ensuring that opportunities exist for collaboration among other OAICs and other NIA programs and centers. The total impact of an OAIC’s activities on progress in the selected field(s) should be a major criterion in selection of the focus area and will be a major criterion in peer review and program evaluation.

To capitalize on important new research opportunities within their institutions, OAICs may also support a limited amount of activity in their cores on topics other than those in their area of focus (see below). Applicants who anticipate providing such support should propose a system for identifying these opportunities and needs and for selecting core activities to address them.

Cognitive and Behavioral/Social Research as an Area of Focus. Cognitive or behavioral/social research should not be the major focus of an OAIC, as these areas are more appropriate for other NIA programs that also use the Center mechanism. However, where appropriate, OAICs are encouraged to support a multidisciplinary approach that includes research in these areas as they relate to the theme or focus of the OAIC.

Health Services Research as an Area of Focus. Research to determine effects of organizational or operational patterns of health practices or services, or the use of new or different types of healthcare providers, is generally appropriate for an OAIC or a component of an OAIC, provided the research is designed to:

Visit our Institutionally Limited Submission webpage for updates and other announcements.