University of Southern California

Research

RFA-AI-16-027: T Cell Reagent Research for the Study of Allergic Diseases (U19)

Slots:                                                   1              
LOI:                                                   February 3, 2017
Internal Deadline:                       Contact the Office of Research if interested.
External Deadline:                     March 3, 2017, 5pm
Award Information:                       
Type:  Cooperative Agreement
Estimated Number of Awards: 2 – 3
Anticipated Amount: $3,000,000

Submission Process:                  PIs must submit their application as a Limited Submission through the Office of Research Application Portal: https://app.wizehive.com/webform/USCgrants

Materials to submit:

Link to Award:                         http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-16-027.html

Who May Serve as PI:             Standard NIH requirements.

Purpose:

This FOA is seeking applications from single institutions, or consortia of institutions, proposing research to understand the role of allergen epitope-specific T-cell responses in the pathogenesis and treatment of allergic diseases including allergic rhinitis, asthma and food allergy, by utilizing allergen epitope-specific reagents.   Identification, characterization and validation of new T-cell epitopes for allergens that have not been previously extensively examined (e.g. fungal allergens or food antigens such as milk), will also be supported under this FOA. Applicants are encouraged to submit multi-project research programs that propose to study immune responses to allergens at the level of epitope-specific T cell subsets, including comparative or interventional studies in humans.  Applicants are also encouraged to capitalize on the availability of allergen T cell epitopes, including those available through the NIAID-funded Immune Epitope Database and Analysis Resource (IEDB).

Visit our Institutionally Limited Submission webpage for updates and other announcements.