University of Southern California


RFA-AI-20-064: A Multidisciplinary Approach to Study Vaccine-elicited Immunity and Efficacy against Malaria (U01 Clinical Trial Not Allowed)

Slots:                                        1

Internal Deadline:                      November 13, 2020

LOI:                                          30 days prior to the application due date

External Deadline:                     February 8, 2021

Award Type:                              Cooperative Agreement

Estimated Number of Awards:    3-5

Anticipated Amount:                    NIAID intends to commit $5M in FY 2022 to fund 3-5 awards.

Process for Limited Submissions: PIs must submit their application as a Limited Submission through the Office of Research Application Portal: For all competitions mentioned in the digest, select the ‘Limited Submission’ option at the top to submit.

Materials to submit include:

(1) Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.

(2) CV – (5 pages maximum)


Who May Serve as PI:                    Standard NIH eligibility requirements.

Purpose:                                   The purpose of this initiative is to support research to advance understanding of the underlying immune mechanisms that contribute to malaria vaccine-elicited protection or vaccine hypo-responsiveness in endemic regions by capitalizing on recent research advances in systems vaccinology and systems immunology as well as emerging opportunities in data science and informatics. Multidisciplinary science and collaboration among investigators from the malaria vaccine research field and other relevant scientific areas are highly encouraged. The goal is to identify host signatures and mechanistic factors that influence malaria vaccine performance in endemic regions to guide and improve future vaccine design and evaluation.


Visit our Institutionally Limited Submission webpage for more updates and other announcements.