RFA-AR-18-004: NIAMS Rheumatic Diseases Research Resource-based Centers (P30)
Internal Deadline: Contact the Office of Research if interested.
LOI: 30 days prior to the application date.
External Deadline: October 3, 2017, 5pm PDT
Award Information: Type: Grant
Estimated Number of Awards: 3
Anticipated Amount: $500,00K in direct costs per year for a maximum of 5 years.
Submission Process: PIs must submit their application as a Limited Submission through the Office of Research Application Portal: https://app.wizehive.com/webform/USCgrants
Materials to submit:
- Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.
- CV – (5 pages maximum)
Link to Award: https://grants.nih.gov/grants/guide/rfa-files/RFA-AR-18-004.html
Who May Serve as PI: Standard NIH eligibility requirements.
The focus of the Center is determined by the Program Director/Principal Investigator (PD/PI) and may encompass basic, translational, and/or clinical research. For this particular announcement, the Center focus is restricted to rheumatic diseases research. The focus may be very broad, e.g. mechanisms of autoimmunity underlying rheumatic disease, and serve a diverse group of investigators that share the need for critical shared core services. Alternatively, a Center may have a narrow disease or biology focus or theme. In some cases, the relevant research community may share a highly specialized resource such as a well-defined patient cohort with associated patient data and biospecimens and/or may share a need for highly specialized technologies and services (e.g. advanced imaging or single cell analysis). However, in all cases the focus of the Center must be within the NIAMS mission. Potential PDs/PIs are strongly encouraged to contact the Scientific/Research Contact listed in Section VII. Agency Contacts early in the application planning process to discuss NIAMS mission relevance.
Each Center must include one or more Resource Cores. For the purpose of this FOA, examples of Resource Cores include, but are not limited to, Cores providing the following:
- A technology that lends itself to standardized procedures, automation or preparation in large batches (e.g., histology, tissue culture, biobanking, high throughput sequencing, genotyping, and other genomic, epigenomic, and microbiomic assays) or that requires complex instrumentation (e.g. electron microscopy, flow cytometry, confocal microscopy, intravital microscopy, whole animal imaging, and mass spectrometry).
- Animal preparation (including transgenic, knockout, and other forms of genetic engineering/gene editing) and care.
- Highly specialized technologies, tools, and expertise such as epidemiology, outcomes, genetics, medical informatics, bioinformatics, biostatistics, systems biology, pharmacogenomics, clinical trial design and support, regulatory affairs, etc.
- Critical infrastructure to support broad sharing of accessible pre-existing patient cohorts and registries as appropriate, including appropriately-consented patient samples and associated clinical data.
The Administrative Core has oversight responsibility for the entire Resource-based Center (P30) and also plans and carries out activities that promote the goals of the Center.
The following are examples of additional goals that would be appropriate for a Resource-based Center. This list is neither mandatory nor inclusive. PDs/PIs are encouraged to propose other innovative goals.
- Provides leadership at an institutional or broader level for research on the topic of focus by the Center
- Expands the research community by attracting new investigators and established investigators from other fields
- Enhances the research environment and promotes synergistic collaborations and/or interdisciplinary research
The Administrative Core must include an Enrichment Program that is designed to expand the research community and/or promote innovative research on the topic of focus of the Center.
Visit our Institutionally Limited Submission webpage for updates and other announcements.