RFA-DK-19-011: Central Coordinating Site for the Polycystic Kidney Disease Research and Translation Core Centers (U24 Clinical Trial Not Allowed)

Slots:                                                     1

Internal Deadline:                           Contact the Office of Research if interested.

LOI:                                                        October 21, 2019

External Deadline:                          November 21, 2019

Award Information:                        Type: Cooperative Agreement

Estimated Number of Awards: 1

Anticipated Amount: NIDDK intends to commit $900,000 in FY 2020 to fund one Central Coordinating Site award.

Budgetary Requirements:           Application budgets are limited to $600,000 in direct costs per year for a maximum project period of 5 years.

Submission Process:                     PIs must submit their application as a Limited Submission through the Office of Research Application Portal: https://app.wizehive.com/webform/USCgrants

Materials to submit:

• Single Page Proposal Summary (0.5” margins; single-spaced; font type: Arial, Helvetica, or Georgia typeface; font size: 11 pt). Page limit includes references and illustrations. Pages that exceed the 1-page limit will be excluded from review.
• CV – (5 pages maximum)

Link to Award:                                  https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-19-011.html

Who May Serve as PI:                   

The CCS (Central Coordinating Site) Director is required to have an established record of external funding and research accomplishment but is not required to have a background in PKD research.

Purpose:

This Funding Opportunity Announcement (FOA) requests applications for the Central Coordinating Site (CCS) for the Polycystic Kidney Disease (PKD) Research and Translation Core Centers (RTCC). The CCS is expected to work collaboratively with four RTCCs as part of the PKD Research Consortium and serve as a national resource for the larger research community. The CCS will provide central administrative and communications support for the Consortium. All activities within the Consortium are expected to address the overall goal of improving our understanding of the pathogenesis, progression, prevention and clinical management of PKD through enhanced sharing of resources and establishment of a robust research community. This FOA is a companion announcement to RFA-DK-19-010: Polycystic Kidney Disease Research and Translation Core Centers (U54).

The overall goal of the CCS is to organize and facilitate the activities of the PKD Research Consortium, under the direction of the PKD Research Consortium Steering Committee, to achieve the following objectives:

• Facilitate sharing of resources and data within the PKD Research Consortium and with the wider PKD research community,
• Develop a multipronged communication plan for disseminating the information about the research resources and methods offered through the RTCCs to the wider PKD research community,
• Organize, support and facilitate the education and outreach activities of the PKD Research Consortium,
• Develop, support and execute the Pilot and Feasibility Program to encourage new investigators in the PKD field,
• Develop and manage a website for internal and external communication,
• Plan, organize and support at least one annual face-to-face meeting for the PKD Research Consortium with a portion of the meeting open to the entire PKD research community,
• Provide centralized administrative support, including coordination of Material Transfer Agreements across the Consortium,
• Identify fixed and variable costs and establish procedures for negotiation of third party agreements or selection of subawards/subcontractors (i.e. clinical/research laboratories, biospecimen repositories, etc.), with involvement of NIDDK Technology Advancement Office, and develop processes to efficiently administer and manage same throughout the project, and
• Schedule and coordinate web-based conference calls and webinars.

Project Organization

The PKD Research Consortium will consist of up to four RTCCs and a CCS. Each RTCC and the CCS will be led by their respective Directors. The RTCCs and the CCS will be considered equal partners in the Consortium with complementary roles. The coordinated efforts of the RTCCs and the CCS will be overseen by the PKD Research Consortium Steering Committee composed of RTCC Directors, the CCS Director and NIDDK program staff. All members of the Consortium will meet monthly via conference calls, and annually at a face-to face meeting in Bethesda, MD. The first meeting that will establish the goals of the Consortium will be held on September 14th, 2020 in Bethesda, MD.

The NIDDK will utilize an External Experts Panel (EEP) to monitor research efforts and advise the Institute on the progress of the PKD Research Consortium. Applications for the RTCCs are solicited through a separate, companion FOA (RFA-DK-19-010). Investigators with appropriate expertise may apply to either or both RFA-DK-19-010 and RFA-DK-19-011. Potential applicants are encouraged to contact the Program Official named in Section VII to discuss their potential applications.

Visit our Institutionally Limited Submission webpage for updates and other announcements.