Virus-Related Research Resources
USC COVID-19 Research UPDATED 4/01
COVID-19 Federal Funding Opportunities UPDATED 3/31
COVID-19 Non-Federal Funding Opportunities UPDATED 3/31
USC Virus-Related Core Facilities UPDATED 4/01
Information about 3D-Printed Face Masks & Shields
COVID-19 High Performance Computing Consortium
The Trump administration has unveiled a new initiative to help researchers worldwide harness a range of America’s most powerful high-performance supercomputing resources to deliberately accelerate new discoveries in the fight against COVID-19. Scientists can tap into 16 of America’s top computing systems. Learn more at COVID-19 HPC Consortium.
COVID-19 Open Research Dataset (CORD-19)
In response to the COVID-19 pandemic, the Allen Institute for AI has partnered with leading research groups to prepare and distribute the COVID-19 Open Research Dataset (CORD-19), a free resource of over 29,000 scholarly articles, including over 13,000 with full text, about COVID-19 and the coronavirus family of viruses for use by the global research community. Learn more at SemanticScholar.org.
Dimensions (COVID-19 Research)
Digital Science wants to support the global research effort to manage and minimise the impact of COVID-19. For researchers, early knowledge and access to research being carried out and published is critical. In order to facilitate this, they’re able to free people from the constraints of specific applications and platforms by providing all relevant content on COVID-19 in Dimensions as a single export file, updated once every 24 hours, to make sharing and distributing this research information easier. The file contains the details of (and links to) all relevant publications, data sets and clinical trials.
Johns Hopkins Coronavirus Map & Resource Center
The map was first shared publicly on Jan. 22. It was developed to provide researchers, public health authorities, and the general public with a user-friendly tool to track the outbreak as it unfolds. All data collected and displayed are made freely available through a GitHub repository, along with the feature layers of the dashboard, which are now included in the ESRI Living Atlas. Learn more at coronavirus.jhu.edu.
USC Libraries: Coronavirus (COVID-19)
Resources for COVID-19 information at USC Libraries including Public Health National & International Government Coronavirus Resources for Health Professionals, Coronavirus Research Portals, and Other Coronavirus Resources for Healthcare Professionals. Learn more at libguides.usc.edu/coronavirus.
Eric Topol’s Twitter
Eric Topol is an American cardiologist, geneticist, author, and scientist. He is the Founder and Director of the Scripps Research Translational Institute in La Jolla, California. Follow him at twitter.com/EricTopol.
Department of Commerce (DOC)
ADDED 3/30! National Institute of Standards and Technology (NIST) invites Manufacturing USA institutes to propose high-impact projects designed to respond to the COVID-19 pandemic. Learn more at NIST Manufacturing USA National Emergency Assistance Program.
Department of Energy (DOE)
3/17 – The U.S. Department of Energy (DOE) encourages you to consider scientific questions that underpin COVID-19 response and that the research community may answer using DOE user facilities, computational resources, and enabling infrastructure. Learn more at DOE Seeking Input and Collaboration on Science and Technology Response to COVID-19.
3/12 – DOE is asking for your ideas about how DOE and the National Labs might contribute resources to help address COVID-19 through science and technology efforts and collaborations. Learn more at Department of Energy Letter Addressing Coronavirus.
Health and Human Services (HHS)
ADDED 3/31! Aging and Disability Resource Centers (ADRC) through a coordinated No Wrong Door System infrastructure provide the foundation to support the most venerable populations during such crisis. This additional funding will help states across the country increase capacity and support resource allocation to ensure state and community level coordination to immediately respond to pressing needs related to the COVID-19 pandemic. Learn more at HHS-2020-ACL-CIP-NWIG-0431.
3/26 – Agency for Healthcare Research and Quality (AHRQ) intends to publish a new funding opportunity announcement using the R01 mechanism to support novel, high-impact studies evaluating health system and healthcare professional responsiveness to COVID-19. Learn more at NOT-HS-20-008.
3/26 – Agency for Healthcare Research and Quality (AHRQ) intends to publish a new funding notice allowing requests for urgent revision supplements to existing AHRQ grants and cooperative agreements to address health system responsiveness to COVID-19. Learn more at NOT-HS-20-007.
3/6 – Department of Health and Human Services (HHS) has updated a broad agency announcement (BAA) to focus specifically on products to diagnose, prevent or treat coronavirus infections. Learn more at HHS Solicits Proposals for Development of Medical Products for Novel Coronavirus.
MSI STEM Research & Development Consortium (MSRDC)
ADDED 3/31! In response to COVID-19, the United States Government has prioritized $9 billion in funding in response to this new disease. COVID-19 presents the nation with a challenge and an opportunity for innovative research solutions. In response to the government’s recent appropriation of funds, we are requesting your research capabilities for a number of federal agencies. Learn more at MSRDC Call to Action to Combat COVID-19.
National Institutes of Health (NIH)
3/27 – The purpose of this supplement is to provide support for the conduct of worker-based training to prevent and reduce exposure of hospital employees, emergency first responders, and other workers who are at risk of exposure to Coronavirus through their work duties. Learn more at NOT-ES-20-014.
3/27 – National Center for Advancing Translational Sciences (NCATS) is issuing this Notice of Special Interest (NOSI) to highlight the urgent need for research on the 2019 novel coronavirus (SARS-CoV-2) and the disease it causes, i.e., “coronavirus disease 2019” (COVID-19). NCATS is particularly interested in projects that repurpose existing drugs or biologics (existing therapeutics) that have already begun or completed a Phase I clinical trial. Learn more at NOT-TR-20-012.
3/27 – National Institute of Allergy and Infectious Diseases (NIAID) is issuing this Notice of Special Interest (NOSI) to highlight the need for research on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Coronavirus Disease 2019 (COVID-19). NIAID is particularly interested in projects focusing on viral natural history, pathogenicity, transmission, as well as projects developing medical countermeasures and suitable animal models for pre-clinical testing of vaccines and therapeutics against SARS-CoV-2/COVID-19. Learn more at NOT-AI-20-031.
3/25 – National Institute of General Medical Sciences (NIGMS) is issuing this Notice of Special Interest (NOSI) to highlight the urgent need for research on SARS-CoV-2 and Coronavirus Disease 2019 (COVID-19). Learn more at NOT-GM-20-025.
3/25 – National Institute of Allergy and Infectious Diseases (NIAID) is issuing this Notice of Special Interest (NOSI) to highlight the need for research on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Coronavirus Disease 2019 (COVID-19). NIAID is particularly interested in projects focusing on viral natural history, pathogenicity, transmission, as well as projects developing medical countermeasures and suitable animal models for pre-clinical testing of vaccines and therapeutics against SARS-CoV-2/COVID-19. Learn more at NOT-AI-20-034.
3/24 – National Center for Advancing Translational Sciences (NCATS) has issued this Notice of Special Interest (NOSI) to highlight the urgent need for research on the 2019 novel Coronavirus (COVID-19). NCATS is particularly interested in projects focusing on the use of informatics solutions to diagnose cases and the use of CTSA-supported core resources (e.g., advanced scientific instruments, highly-specialized facilities, and regulatory expertise) to facilitate research on COVID-19 and advance the translation of research findings into diagnostics, therapeutics, and vaccines. Learn more at NOT-TR-20-011.
3/19 – NIH has issued a notice to highlight the urgent need for research on the 2019 Novel Coronavirus (2019-nCoV, also known as COVID-19). National Institute on Drug Abuse (NIDA) is especially interested in research collecting and examining data on the risks and outcomes for COVID-19 infection in individuals suffering from substance use disorders. Learn more at NOT-DA-20-047.
3/17 – NIH has issued a notice to highlight the urgent need for research on COVID-19 and on biological effects of its causative agent, SARS-CoV-2. Topics of specific interest to National Heart, Lung, and Blood Institute (NHLBI) include host response, associations with heart, lung, and blood diseases, potential impacts on transfusion safety, and clinical outcomes of infected individuals. Learn more at NOT-HL-20-757.
2/6 – NIH has issued a notice to highlight the urgent need for research on COVID-19. National Institute of Allergy and Infectious Diseases (NIAID) is particularly interested in projects focusing on viral natural history, pathogenicity, transmission, as well as projects developing medical countermeasures and suitable animal models for pre-clinical testing of vaccines and therapeutics against COVID-19. National Institute of General Medical Sciences (NIGMS) is specifically interested in incorporation of data from COVID-19 into ongoing research efforts to develop predictive models for the spread of Coronaviruses and related pathogens. Learn more at NOT-AI-20-030. This will be rescinded as of 04/08/2020.
National Science Foundation (NSF)
3/5 – The Office of Advanced Cyberinfrastructure (OAC) within the Directorate for Computer and Information Science and Engineering is inviting RAPID proposals and supplemental funding requests to existing awards that address COVID-19 challenges through data and/or software infrastructure development activities. Learn more at NSF 20-055.
3/4 – NSF is accepting proposals to conduct non-medical, non-clinical-care research that can be used immediately to explore how to model and understand the spread of COVID-19, to inform and educate about the science of virus transmission and prevention, and to encourage the development of processes and actions to address this global challenge. Learn more at NSF 20-052. They’ve posted a FAQ for NSF 20-052.
Office of Science and Technology Policy
3/16 – In response to the COVID-19 pandemic, the Allen Institute for AI has partnered with leading research groups to prepare and distribute the COVID-19 Open Research Dataset (CORD-19), a free resource of over 29,000 scholarly articles, including over 13,000 with full text, about COVID-19 and the coronavirus family of viruses for use by the global research community. The White House has issued a call to action to the Nation’s artificial intelligence experts to develop new text and data mining techniques that can help the science community answer high-priority scientific questions related to COVID-19. Learn more at Call to Action to the Tech Community on New Machine Readable COVID-19 Dataset.
USC Office of Research
In response to the current pandemic of COVID-19 specifically, and more broadly, to the need to addresses critical gaps in knowledge and response methods, tools, technologies, and strategies related to viral diseases and disease outbreaks, the Office of Research is issuing a Zumberge Special Solicitation – Epidemic & Virus Related Research and Development Award, jointly sponsored by the USC Office of the Provost and the USC Stevens Center for Innovation. Learn more at Zumberge Special Solicitation.
The Office of Research has expanded the areas of research interest eligible to be submitted to the Provost New Strategic Directions in Research Award to include all areas of USC research and scholarship that may provide a broader perspective on viral diseases and the detection and response to their outbreaks. Eligible topics include biomedical and clinical research and development, as well as research and development broadly related to public health, legal, economic, societal, and fiscal implications, among others. Learn more at PNSDRA.
California Institute for Regenerative Medicine (CIRM)
ADDED 3/31! Given the growing surge of COVID-19 cases in California and throughout the world, CIRM is issuing this special announcement to support promising discovery, preclinical and clinical trial stage projects that could quickly advance treatments to COVID-19 patients in need. Learn more at Special Call for COVID-19 Projects.
3/20 – LifeArc has made available an initial £10M for the identification of therapeutics that can be rapidly deployed to treat COVID-19. The aim is to run trials in patients during the current epidemic. It is anticipated that applications will be for funding to repurpose one or more drugs that are generic, already licensed, or are in late stage development for another indication. Learn more at LifeArc: Coronavirus (COVID-19) Therapeutics.
Massachusetts Institute of Technology (MIT)
3/5 – MIT Solve is seeking tech innovations that can slow and track the spread of an emerging outbreak, for example by improving individual hygiene, developing low-cost rapid diagnostics, analyzing data that informs decision making, and providing tools that protect health workers. Solve is also seeking solutions that focus on preventative and mitigation measures that strengthen access to affordable primary healthcare systems, enhance disease surveillance systems, and improve healthcare supply chains. Learn more at MIT Solve: Health Security & Pandemics Challenge.
The CoVent-19 Challenge
ADDED 3/30! The CoVent-19 Challenge is fostering the innovation of a rapidly deployable, minimum viable mechanical ventilator for patients with COVID-19 related ventilator-dependent lung injury. The CoVent-19 Challenge is an open innovation 8-week Grand Challenge for engineers, innovators, designers, and makers. Learn more at The CoVent-19 Challenge.
BSL3 Containment Facility with In Vitro and In Vivo suites for research utilization. Services include SOP training, work flow guidance, sample storage and basic laboratory equipment. All research involving COVID-19 virus (SARS-CoV-2), including clinical specimens that might contain the virus, must be reviewed and approved by the USC Institutional Biosafety Committee.
Covid-19 Health Tracking Poll to online panel of both National and LA County residents
The CPPE provides ala carte and comprehensive peptide synthesis and purification services for the USC and general community.
For the new test kit and compound design and development, the Center provide instruments including Microplate reader, Biacore, ITC to study the interaction between protein-protein, protein-compound and protein-DNA.
High Content Screening (HCS) and High Throughput Screening (HTS)
The BERD team can assist investigators with the conduct, interpretation and summary of statistical analyses.
CRI provides services enabling complete access and analysis of patient data from the electronic medical records of Keck Medicine of USC, Children’s Hospital of Los Angeles, and the Los Angeles Department of Health Services.
Clinical Research Coordinator Pool who provide study-related services ranging from regulatory document preparation, participant recruitment, data collection and entry, and study monitoring.
The CTU employs highly qualified research staff to meet all of your human study needs, such as skilled research nurses, research phlebotomists, lab technicians, and radiology technicians.
Live imaging of infected cells and tissues, including metabolic imaging. Stryker Treacheoscope for metabolic imaging in human airways. Olympus Bronchoscope for metabolic imaging of airways of animal models.
USC COVID-19 Biospecimen Repository
Procurement, processing, and storage of biospecimens from patients and appropriate controls to support researcch on COVID-19 in a CAP/CLIA certified environment. Biospecimens to include bronchial washings and brushings, bronchial FNA and core biopsy specimens, whole blood, serum, plasma, peripheral blood mononuclear cells, other as requested.