The Imaging Genetics Center (IGC) uses advanced “big data” methods to study over 20 major diseases of the brain — from Alzheimer’s disease and Parkinson’s disease to disorders of brain development, psychiatric illnesses, and neurogenetic disorders. They co-founded a worldwide consortium of over 900 scientists from 40 countries to study the brain, called the ENIGMA Consortium; they have published the largest neuroimaging studies of 10 major brain disorders, including schizophrenia, bipolar disorder, major depressive disorder, PTSD, and substance use disorders, revealing characteristic profiles of brain abnormalities in each disorder, and investigating factors that affect them.