University of Southern California

Research

Biomedical, Life Sciences & Materials Imaging

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Cell and Tissue Imaging Core

The Cell and Tissue Imaging Core is available by appointment 24 hr/day for sample processing, technical assistance and training in the operation of imaging equipment. Services include: tissue processing, thin sectioning , embedding, cryosectioning, immunostaining, paraffin embedding, digital photomicroscopy, digital slide scanning, SEM imaging, and TEM imaging and computer aided graphics. Training and assistance in the use of instruments and associated technical procedures is provided by appointment and in scheduled in-service training sessions.

Health Sciences Campus
Doheny Eye Institute
DVRC Building Room 214
1355 San Pablo St.
Los Angeles, CA 90089
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Cellular Imaging Core

The Cellular Imaging Core houses light microscopy and digital image processing equipment to support cell biology research. Services include: consultation on the design, execution, and analysis of fixed and live cell imaging experiments as well as training in the utilization of Core facilities. Equipment includes: a Zeiss (LSM 710 Inverted Confocal, an Axioplan Upright and Axio Observer), a Leica (DM RXA Upright Fluorescence and MZFLIII Stereo), and a Carv II Spinning Disk Live Cell Imaging Confocal.

Children’s Hospital Los Angeles, CHLA
Smith Research Tower
4546 Sunset Blvd
Los Angeles, CA 90027
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Center for Electron Microscopy and Microanalysis

CEMMA provides research tools for imaging, visualization, and analysis of nano-scale features and structures, both man-made and natural, including biological structures. Services include: full-time technical staff support providing training and assistance with advanced applications. Equipment includes: scanning and transmission electron (TEM, SEM, and FIB) and light (super-resolution, GE Delta Vision OMX) microscopes.

University Park Campus
814 Bloom Walk, CEM 101B
Los Angeles, CA 90089-0101
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Cognitive Neuroscience Imaging Center

The Dana & David Dornsife Cognitive Neuroscience Imaging Center pursues structural and functional brain imaging studies using state of the art techniques, to contribute to the development of future brain imaging modalities and to disseminate knowledge about the brain, the mind and neuroimaging. Equipment & services include: a 3T Siemens TRIO scanner with associated support equipment; a BIOPAC MR-Compatible Physiological Data Acquisition System and an ASL 504 LRO Eye Tracker.

University Park Campus
Neuroscience Imaging Center
3520A McClintock Ave
Los Angeles, CA 90089-1061
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Image Processing and Informatics Lab

The Image Processing and Informatics (IPI) Laboratory utilizes Biomedical Imaging and Informatics Technologies to train and educate scientists and physicians in clinical R&D services related to medical imaging and informatics. Services and research areas include: computer-aided diagnosis (CAD), bone age assessment, development of data grids (clinical trials, small animal imaging, imaging security and combination teleradiology and PACS operations) and radiation therapy informatics. Equipment includes: a PACS Simulator, a Fault-tolerance Server, Data Grid, PACS workstations, CAD servers, and connections to two clinical PACS.

University Park Campus
Annenberg Research Park
734 West Adams Blvd.
Los Angeles, California 90089
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Molecular Imaging Center – Small Animal Imaging

The USC Molecular Imaging Center focuses on the translational needs of investigators to allow in vivo imaging of disease processes and development of new molecular therapeutics and diagnostics, providing support to research studies of small animals for a variety of applications. Equipment and services include: training and/or assistance with study design, imaging procedures, imaging probe design, and image analysis are provided in the use of microCT, microPET, micro-ultrasound, optical imaging, radio chemistry as well as radiography and autoradiography systems.

Health Sciences Campus
Clinical Science Center
2250 Alcazar Street, CSC/IGM 103
Los Angeles, CA 90033-9061
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Multi-Photon Microscopy Core

The Multi-Photon Microscopy Core provides in vivo imaging of intact organs in small animals with high temporal and subcellular resolution, ideal for studying (patho)physiological processes in health and disease. Equipment includes: a Leica TCS SP5 AOBS Multi-Photon Confocal Microscope System.

Health Sciences Campus
Zilkha Neurogenetic Institute
1501 San Pablo Street, ZNI 313
Los Angeles, CA 90089
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Neuroplasticity and Imaging

Research at the Neuroplasticity and Imaging Lab uses Transcranial Magnetic Stimulation (TMS) to investigate brain-behavior relationships during motor skill learning and motor control in non-disabled and brain-injured individuals. Equipment and services include: the lab maintains a range of TMS technologies for research use (Magnetic stimulation system, Magstim 2002, Bistim2, Magstim Rapid2, 2nd Generation Remote Coils, Custom Coils, Double 70mm Cooled Coil System, Brain navigation system, EMG recording system, DataWizard).

Health Sciences Campus
Center for Health Professions
1540 Alcazar Street, CHP 155
Los Angeles, CA 90089-9006
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Research Imaging Core at the Saban Research Institute

The Research Imaging Core at the Saban Research Institute, CHLA, is a full-service in vivo imaging laboratory providing non-invasive capabilities for use on mammalian models. Equipment and services include: data collection, processing and interpretation and access to core instrumentation: a Xenogen for optical imaging (bioluminescence and fluorescence), a 7T micro Magnetic Resonance Imager (MRI), a micro X-ray Computed Tomography (CT) instrument and a Gamma Medica combined CT micro Single Photon Emission Computed Tomography (SPECT).

Children’s Hospital Los Angeles, CHLA
Saban Institute Small Animal Imaging Research Center
4661 Sunset Blvd.
Los Angeles, CA 90027
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Translational Imaging Center

The Translational Imaging Center (TIC) and the Light Microscopy Imaging Center bring together advanced light and fluorescence microscopy systems, providing facilities and instruments for scientists engaged in translational research. The TIC is also focused on developing new technologies for automating and providing advanced imaging technologies. Equipment includes: confocal and two-photon OPO fluorescence microscopes and state of the art image analysis software.

University Park Campus
Ray R. Irani Hall
1050 Childs Way, RRI324
Los Angeles, CA 90089
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USC Imaging Core

The USC Imaging Facility at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research is equipped with a wide range of microscopes to study high-resolution cellular dynamics in diverse systems such as mouse embryos, living zebrafish and human embryonic stem cell cultures. Equipment and services include: confocal and wide-field microscopes. While priority of use is given to researchers within the Center, collaborative efforts with outside laboratories are highly encouraged.

Health Sciences Campus
Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell
1425 San Pablo Street
Los Angeles, CA 90033
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Video Tracking Core

The USC Video Tracking Core (VTC) facility provides specialized research video services to USC and non-USC researchers. High-speed video combined with specialized lighting and software enables us to assay 3D movement, behavior patterns, gene expression and metabolite levels in free-moving animals, including Drosophila melanogaster and C. elegans, for periods ranging from <1/30 second to months. Services include: Analysis of movement and behavior patterns; Quantification of fluorescent transgenic reporter molecules, including green-fluorescence (GFP), red-fluorescence, blue-fluorescence and others; Quantification of fluorescent transgenic reporter molecules in specific tissues, including CNS, muscle, liver, heart and intestine; Small molecule testing for effects on behavior, gene expression and metabolite levels; Quantification of Drosophila life span and healthspan; Training and education.

University Park Campus
Ray R Irani Hall (RRI 219C)
1050 CHILDS WAY, Bldg. #291
Los Angeles, CA 90089
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X-Ray Crystallography Facility

The purpose of the X-Ray Crystallography Facility is to structurally characterize single-crystal samples of organic, inorganic, and organometallic compounds using X-ray diffraction. Equipment and services include: a Bruker APEX DUO single-crystal diffractometer equipped with an APEX2 CCD detector, Mo fine-focus and Cu micro-focus X-ray sources and a Rigaku Ultima IV powder/thin film diffractometer to conduct rapid structural analysis. It is capable of handling samples that are sensitive to air, moisture, and/or temperature and the core provides training for users to conduct their own experiments.

University Park Campus
John Stauffer Science Lecture
837 Bloom Walk
Los Angeles, CA 90087
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Research Calendar

See all events in the USC Research Calendar.