The USC-Buck Nathan Shock Center of Excellence in the Biology of Aging is a fully integrated multi-institutional center focused on training the next generation of geroscientists and providing access to cutting edge geroscience technologies to investigators across the nation. The USC-Buck NSC is devoted to forging a deeper understanding of how and why aging processes cause disease in order to advance the translation of basic research on aging into effective preventions and therapies. Specialized cores provide services to all Shock Center members, as well as for-fee services to the community at large.