University of Southern California

Research

Medicine and Health

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Alzheimer’s Disease Research Center

The Alzheimer Disease Research Center at USC is supported by the National Institutes of Health to conduct research on memory problems and aging. Our studies include observational studies that follow participants over time while examining changes that may occur with age, and therapy studies such as exercise training, medications and vaccines. Our goals are to understand the biological changes that may precede worsening memory and to assess whether new treatments including drugs may be helpful in preventing memory or improving memory loss.

Alzheimer’s Therapeutic Research Institute

The USC Alzheimer’s Therapeutic Research Institute (USC ATRI) is dedicated to the development of effective treatments for Alzheimer’s disease through innovative, collaborative, multicenter clinical trials. ATRI’s collaboration with Keck investigators facilitates rapid progress in data sharing and analytical methods central to the drug development process.

Biomimetic MicroElectronic Systems

Funded by the National Science Foundation, the goal of this center is to develop the science and engineering of novel biomimetic microelectronic systems based on fundamental principles of biology. The newly developed systems will allow bidirectional communication with tissue and by doing so enable implantable/portable microelectronic devices to treat presently incurable human diseases such as blindness, paralysis and memory loss.

Center for Applied Molecular Medicine

This center comprises a multidisciplinary team of investigators dedicated to furthering the development and use of proteomic technologies to guide doctors in patient management decisions. The center is based within the Department of Medicine.

Center for Applied Network Analysis

The Center for Applied Network Analysis (CANA) hosts a twice monthly, two-hour lab meeting in which students, postdoctoral candidates and faculty present work in progress. CANA meetings cover a diverse set of topics centered around conducting research using the social network approach. CANA also organizes workshops on technology and techniques for conducting analysis.

Center for Body Computing

With a mission to modernize health care through technology to make it more personal, affordable and accessible for all, the USC Center for Body Computing was founded in 2006 as one of the nation’s first academically-based digital health research and innovation centers. By leveraging digital technology to provide personal and continuous care, the USC CBC conducts clinical research to establish safety and efficacy of these emerging technologies.

Center for Craniofacial Molecular Biology

The Herman Ostrow School of Dentistry of USC’s Center for Craniofacial Molecular Biology is a unique facility that unites world-class researchers in a variety of disciplines centered around structures of the craniofacial region. Since its inception in 1991, CCMB has been home to several major discoveries and has attracted top researchers from around the world.

Center for Drug Discovery and Development

Housed at the School of Pharmacy, the USC Center for Drug Discovery and Development assembles a diverse group of scientists from throughout the university with expertise in all aspects of the design and synthesis of potential pharmacological breakthroughs. The Center benefits from a team of pharmacologists, toxicologists, and pharmaceutical and regulatory scientists skilled at expediting evaluation of a wide range of therapeutics to bring new innovations more quickly to patients who need them, while assuring safety and effectiveness.

Center for Genetic Epidemiology

The Center for Genetic Epidemiology studies the genetic factors that contribute to disease, with a major focus on diverse populations that have different risks of developing disease. The center also concentrates on the establishment of population-based resources and the development and application of genomic methods for understanding the genetic basis of disease.

Center for Health Equity in the Americas

The Center for Health Equity in the Americas (CenHealth) conducts and promotes research and collaborations that address health equity in vulnerable populations throughout North America, South America, Central America and the Caribbean. CenHealth’s mission is to eliminate health disparities by encouraging and facilitating research in the Americas.

Center for Image Acquisition

The Center for Image Acquisition is an MRI facility housing a Siemens Magnetom Prisma, a new 3 Tesla MRI scanner and a Siemens Magnetom 7T MRI scanner. Opened in 2016, the center is part of the USC Mark and Mary Stevens Neuroimaging and Informatics Institute, which aims to enhance discovery through the application of imaging and information technologies in the study of the brain.

Center for Integrative Connectomics

The Center for Integrative Connectomics, home of the Mouse Connectome Project (MCP), seeks to develop a multimodal, multiscale connectome and cell-type map of the mammalian brain using advanced tracing, imaging and computational methods. The center’s multidisciplinary team develops neuroanatomic and neuroinformatic approaches in order to understand connectivity patterns in both health and disease.

Center for Quantitative Drug and Disease Modeling

The Center for Quantitative Drug and Disease Modeling at the Department of Clinical Pharmacy at the USC School of Pharmacy was founded in 2018, with the purpose of developing a collaborative, cutting-edge academic enterprise focused on state-of-the-art quantitative medicine.

Center for USC-Taiwan Translational Research

The Center for USC-Taiwan Translational Research focuses on promising new work in the fight against cancer. Currently, center scientists are exploring new cancer therapies that target monoamine oxidase (MAO). Dr. Jean Chen Shih, internationally known for her decades-long, foundational exploration on MAO, directs the center.

Children’s Environmental Health Center

This center studies the effects of the environment on human health, concentrating on air quality and the multiethnic populations of California and the Pacific Rim. The center is based within the Department of Preventive Medicine.

Children’s Hospital Los Angeles, Saban Research Institute

Research at CHLA focuses on pediatric diseases and treatments and is ranked as one of the top pediatric research programs in the nation. The Saban Research Institute manages and leads all research endeavors.

Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics

Working at the interface of medicine and engineering, USC Ginsburg IBT’s vision is to transform bioengineered neural interfaces into treatments for patients for whom there is currently no foreseeable cure. Using an interdisciplinary approach, our mission is to further our basic understanding of debilitating neurosensory disorders, ultimately leading to the development of novel diagnostic and treatment options.

Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research

Our investigators are exploring the normal mechanisms that build, maintain and repair our body systems to develop knowledge-based approaches for regenerative medicine. Scientists are researching kidney, liver, neural, blood, cardiovascular, skeletal and skin disease models. The center serves as a hub for USC Stem Cell, which connects researchers in stem cell biology and regenerative medicine across USC.

Free Radical Institute

We aim to tackle the “big questions” in FRBM including such major translational issues as the role(s) of free radicals in: cancer, neurodegeneration, heart disease, stroke, liver disease, rheumatoid arthritis, aging, muscle degeneration, drug design and discovery. nutrition, public health. We seek to build teams of: physician scientists, biochemists/molecular biologists, engineers, gerontologists, pharmacists, dentists, nutritionists, public health experts.

Institute for Addiction Science

By bringing scholars together and providing an infrastructure to stimulate synergy and collaboration, the Institute for Addiction Science (IAS) advances its mission to generate transdisciplinary addiction research and education programs that promote discovery and dissemination of novel and impactful approaches to understanding, preventing, and treating addiction.

Institute for Health Promotion & Disease Prevention Research

The Institute for Health Promotion and Disease Prevention Research (IPR) is an organized research unit of the Keck School of Medicine of the University of Southern California. IPR is recognized for its strength in health behavior and disease prevention research. In fiscal year 2017, the IPR faculty was awarded more than $$ in external funding for research and training from federal, state, and local government agencies.

Institute of Translational Genomics at Keck Medicine of USC

The Department of Translational Genomics and Institute of Translational Genomics at Keck Medicine of USC is focused on translating the molecular study of genes into individual treatment plans. The award-winning, collaborative team intends to redefine and further precision medicine to bring novel technologies and molecular insights to patients.

Institute on Inequalities in Global Health

At the University of Southern California Institute on Inequalities in Global Health, leaders work across disciplines to address the disparities, inequalities and broad determinants of health that impact our world. University-wide and driven by excellence in research, education and action, the institute aims to address those issues that are too complex to have a natural home with any single researcher, department or school.

International Center for Regulatory Science

The D.K. Kim International Center for Regulatory Science is an educational and research institution that provides cross training for individuals with a scientific background to become adept in business and knowledgeable in regulatory science to meet the growing need for professionals with the knowledge and expertise to navigate the complex international regulatory landscape.

Leonard D. Schaeffer Center for Health Policy and Economics

Our vision is to be a premier research institution recognized for innovative, independent research that makes significant contributions to policy and health improvement. Our mission is to measurably increase value in health through evidence-based policy solutions, research excellence, and private and public-sector engagement. With an extraordinary breadth and depth of expertise, the Schaeffer Center has a vital impact on the positive transformation of healthcare.

Mark and Mary Stevens Neuroimaging and Informatics Institute

USC’s Mark and Mary Stevens Neuroimaging and Informatics Institute applies innovative imaging and information technologies to the study of the brain. We share our data and resources with thousands of collaborators around the world.

MESH Academy

The MESH Academy is a joint initiative of the Dean of the Keck School of Medicine of USC and the USC Office of the Provost. The mission of the MESH Academy is to empower the convergence of research in medicine, engineering, sciences and humanities through educational programs, incentives for innovation and entrepreneurship and corporate relations to address challenges in human health and disease.

NIH FaceBase Coordinating Center

FaceBase is a collaborative NIDCR-funded project that houses comprehensive data in support of advancing research into craniofacial development and malformation. It serves as a community resource by curating large datasets of a variety of types from the craniofacial research community and sharing them via this website. One of the missions of this project is to facilitate cooperation and collaboration between the central coordinating center (ie, the Hub) and the craniofacial research community.

NIH GenitoUrinary Development Molecular Anatomy Project Coordinating Center

The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is a consortium of laboratories working to provide the scientific and medical community with tools to facilitate research on the GenitoUrinary (GU) tract.

Research Center for ALPD and Cirrhosis

The center, since its inception in 1999, has devoted its efforts for development and use of clinically relevant animal models to gain novel insights into the molecular mechanisms underlying the predisposition to advanced ALPD. These efforts culminated in recent groundbreaking discoveries which have significantly advanced our understanding of synergistic ALPD caused by alcohol and a second hit.

Research Center for Liver Diseases

The key goal of the Research Center for Liver Diseases is the facilitation and fostering of interdisciplinary collaborative research, which leads to a better understanding of the pathobiology of diseases of the liver and digestive tract and the development of new treatments for these diseases.

Roski Eye Institute

The USC Roski Eye Institute has more than 135 faculty covering all subspecialties of ophthalmology. The USC Roski Eye Institute is one of the leading eye centers in the world studying the burden of vision loss and its impact on quality of life among vulnerable populations such as children and minorities.

Southern California Clinical and Translational Science Institute

The USC School of Pharmacy is a key partner and three USC Pharmacy faculty play leading roles in the National Institutes of Health-funded Southern California Clinical and Translational Science Institute (CTSI), which serves to translate scientific discoveries into new advances in clinical and community health. The Center aims to speed research from laboratories to sustainable public health solutions with a particular focus on improving the health of diverse populations in urban settings such as Los Angeles.

Southern California Clinical and Translational Science Institute (SC CTSI)

Established in 2010, the Southern California Clinical and Translational Science Institute (SC CTSI) is one of 60 NIH-funded Clinical Translational Science Awards with a mandate to increase the efficiency and quality of translational research. SC CTSI helps accelerate scientific discoveries and their application in real-life settings in order to address the specific health needs of urban and diverse populations and improve human health by helping researchers obtain the education, resources and collaborations necessary to translate discoveries into practice.

Southern California Environmental Health Sciences Center

This center studies the effects of the environment on human health, concentrating on air quality and the multiethnic populations of California and the Pacific Rim. The center is based within the Department of Preventive Medicine.

The Diabetes & Obesity Research Institute

The Diabetes & Obesity Research Institute (DORI) at the University of Southern California was established in 2012. The Institute was designed to foster interactions across disciplinary boundaries; embrace methods and techniques from diverse fields of study; and develop effective approaches to risk assessment, prevention and treatment of the international co-epidemics of diabetes and obesity.

USC Edward R. Roybal Institute on Aging

The Roybal Institute advances research whose goal is to enhance optimal aging for persons in minority and low-income communities. The institute builds upon USC’s longstanding tradition of creating socially relevant research, innovating educational practices, influencing policymaking, fostering community-university partnerships and sharing best practices with direct service providers.

USC Gehr Family Center for Health Systems Science

The USC Gehr Family Center for Health Systems Science aims to accelerate the adoption of high-value and equitable health care for the Los Angeles community and nationwide, through science, advocacy and education. The center’s mission is to help collaborating health systems deliver better, more efficient care and to learn about the science of health care delivery in the process.

USC Hastings Center for Pulmonary Research

The USC Hastings Center for Pulmonary Research (HCPR) is making strides to combat lung disease through scientific investigations into the biology of lung injury, repair and regeneration. As part of its mission, HCPR seeks to expand and enhance pulmonary research through the creation of interdisciplinary research programs, enhanced training and career development, and targeted faculty recruitments.

USC Imaging Genetics Center

The Imaging Genetics Center (IGC) is a research team of neuroscientists, engineers, medical doctors and computer scientists who are studying brain imaging, genetics and the connections between them. For 20 years, IGC has made advances in understanding major diseases and disorders of the human brain.

USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI)

The USC Mark and Mary Stevens Neuroimaging and Informatics Institute (INI) aims to enhance discovery through the application of imaging and information technologies in the study of the brain. The Institute is dedicated to excellence in data acquisition, analysis, stewardship and computational innovation for the purpose of biomedical research.

USC Michelson Center Convergent Science Institute in Cancer

CSI-Cancer is aimed at integrating patient, model system, and high-content single cell data to translate clinically observed correlations into a mechanistic understanding of the physical and biological underpinnings of cancer dynamics. The organizing framework of the physical dynamics of cancer at the lab will focus on the spatial distributions and temporal evolution of the disease at the cellular, human, and population scale.

USC Neurorestoration Center

The USC Neurorestoration Center is a multi-institution collaboration for breakthrough discoveries that, for the first time, bring together neural engineering, neuroscience and neurorehabilitation to restore neurological function in the human brain. Driven by patient needs and further refined within our world-class clinical programs, strategies created by the center aim to restore an injured or diseased nervous system by developing new technologies that harness advances in basic neuroscience and neural engineering.

USC Norris Comprehensive Cancer Center

USC Norris Comprehensive Cancer Center scientists work toward a complete understanding of the most fundamental aspects of cancer. The National Cancer Institute (NCI) has designated the USC Norris Comprehensive Cancer Center as one of the nation’s 45 comprehensive cancer centers, a select group of institutions providing leadership in cancer treatment, research, prevention and education.

USC/UKRO Kidney Research Center

USC/UKRO Kidney Research Center (KRC) conducts basic, translational and clinical research into kidney diseases in the United States. KRC’s mission is to promote innovative clinical research that significantly contributes to advances that improve the health of people living with kidney disease.

Zilkha Neurogenetic Institute (ZNI)

The Zilkha Neurogenetic Institute (ZNI), established in 2003, is an integral part of a broader USC neuroscience initiative promoting collaboration between researchers from diverse disciplines. Scientists at the institute reach across boundaries to embrace methods and techniques from other fields of study, identifying new approaches to examine nervous system function so we may all better understand the underlying causes of neurological and psychiatric disorders.